Recently, the research teams led by Professor Aiwen Lei from Wuhan University and Professor Lin He from Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, made a significant breakthrough in asymmetric urea synthesis. Their research results, titled "Synchronous recognition of amines in oxidative carbonylation toward unsymmetrical ureas" were published in the prestigious international journal "Science" on November 15th.   Published in "Science" with the Support of CIQTEK EPR   Unsymmetrical ureas are important compounds widely used in medicine, agriculture, and materials science. The synthesis of unsymmetrical ureas through amine reactions is the most effective method. However, achieving high selectivity in synthesizing unsymmetrical ureas is challenging due to the competitive reactivity of the two amines. So far, no metal-catalyzed method can efficiently and selectively recognize and install multiple amines at the same site.   In their research, the teams deeply analyzed the electron transfer process between copper salts and amines and successfully detected the in situ-generated ammonium radical cation and its captured radical species with DMPO during the reaction. This provided crucial evidence for revealing the copper ion-mediated free radical activation mechanism of secondary amines. Combining the selective nucleophilic activation of primary amines by cobalt catalysts, the teams designed a "synchronous recognition strategy" that achieved efficient carbonylation reactions of a 1:1 molar ratio of two amines, producing highly selective unsymmetrical urea products.   This achievement provides new avenues for the industrial production of unsymmetrical urea compounds and is expected to have broad applications in fields such as medicine and agriculture. It also demonstrates the precise characterization capabilities of the EPR spectrometer developed by CIQTEK, providing strong support for researchers to deepen their understanding of reaction mechanisms and develop innovative synthesis strategies.   The research paper was published in "Science" and can be accessed at the following link: https://www.science.org/doi/10.1126/science.adl0149   A "Timely Rain" that Achieves Customer Satisfaction, Scripting a Success Story   Behind this achievement is a story of collaboration between CIQTEK and the research team. In October 2021, an imported EPR spectrometer at the College of Chemistry and Molecular Sciences, Wuhan University, encountered a sudden malfunction.   After contacting the manufacturer, they learned that the repair would take a long time. This posed a challenge for the experimental work of the faculty and students.   In December of the same year, at the invitation of the faculty, engineers from CIQTEK overcame the challenges posed by the pandemic and arrived on-site to troubleshoot the issue. They quickly identified a problem with the magnet po...

In October 2024, CIQTEK officially launched the AI Electron Paramagnetic Resonance (EPR) Spectrometer. This series of products possesses AI-driven spectrum analysis and intelligent literature correlation and achieves a groundbreaking signal-to-noise ratio of 10,000:1, which is the highest in the field of EPR spectroscopy. For your reference, we have compiled the following questions and answers to address user concerns.   01. Is the AI spectrum analysis function only for simple free radicals? Can it analyze multi-electron systems?   The AI EPR Spectrometer's spectrum analysis function is not limited to simple free radicals and can also analyze complex multi-electron systems. Specifically, it can fit over 90% of free radical samples and support the analysis of multi-electron systems, including metal complexes and multi-component samples. Therefore, whether it's a single type or a more complex multi-electron structure, AI spectrum analysis is capable.   02. What is the source of data for AI spectrum analysis?   The data for the AI-EPR Spectrometer's spectrum analysis comes from multiple authoritative sources. The internal database contains over 24,000 substance components, 250,000 related published literature, and more than 200,000 measured data points from various universities, research institutions, and testing centers. These extensive data sources ensure the accuracy of AI spectrum analysis.   03. How does AI spectrum analysis perform on multi-spin systems?   AI spectrum analysis can effectively handle complex multi-spin systems and accurately distinguish and fit multiple components. However, multi-spin systems involve more complex parameters, which present greater challenges for analysis. Nonetheless, AI spectrum analysis typically provides reliable preliminary results for users' reference.   04. Can AI spectrum analysis analyze metal samples?   AI spectrum analysis can handle the analysis of metal samples. It not only supports the fitting of free radical samples but has also been optimized specifically for metal complexes and multi-component systems. Therefore, the analysis of metal samples, especially those involving paramagnetic metal ions, falls within its capabilities. However, the precision of the results may vary depending on the specific metal and sample complexity.   05. Does AI spectrum analysis support EPR instruments from other brands?   Currently, the AI spectrometric system is not compatible with direct integration and usage of EPR spectrometers from other brands. The current system only supports EPR spectrometers from CIQTEK.   06. If a sample is more complex, such as multi-component with coupling between components, can AI still be used?   For complex samples with multiple components and coupling between them, AI spectrum analysis can certainly provide significant assistance. Leveraging its rich data and intelligent algorithms, it can partia...

The National Conference on Electron Microscopy(CEMS) was held in Dongguan from October 17th to 21st, 2024. The conference attracted nearly 2,000 experts, scholars, and representatives from universities, research institutions, enterprises, and instrument technology companies.     CIQTEK showcased the Focused Ion Beam Scanning Electron Microscope DB550 and the Field Emission Transmission Electron Microscope TH-F120 and conducted live demonstrations on-site, which received wide attention from the attendees.   "Next-Generation On-axis Signal Electron Selective Detection Technology & Progress in Cold FEG Scanning Electron Microscope Development"   Mr. Cao Feng, Vice President of CIQTEK, delivered a keynote speech during the conference, showcasing the company's latest technological breakthroughs and innovative achievements in the field of electron microscopy, and receiving high recognition from the experts present.     To provide users with a tangible experience of the development achievements of high-end electron microscopes and to demonstrate the real performance of the products, CIQTEK once again set up the "Electron Microscope Laboratory" at the conference venue.     With careful arrangement by a professional team, the booth not only recreated a laboratory environment but also realized the live demonstration of the Focused Ion Beam Scanning Electron Microscope DB550 and the Field Emission Transmission Electron Microscope TH-F120. On-site sample preparation and imaging fully showcased the superior performance of domestically produced high-end electron microscopes, attracting a large number of professional visitors for visit exchanges.