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Recently, Zhichao Jin's research team at Guizhou University has demonstrated that heteroatomic anions can be used as super-electron donors to initiate free-radical reactions to easily synthesize 3-substituted benzofurans. The resulting products have broad application prospects in organic synthesis and pesticide development.     The results were published in the prestigious journal Nature Communications under the title "Facile access to benzofuran derivatives through radical reactions with heteroatom-centered super-electron-donors". In the study, CIQTEK's X-band continuous-wave electron paramagnetic resonance spectrometer EPR200-Plus was used to confirm the generation of free radical species in the reaction system.   Benzofurans are among the 100 major cyclic structures widely found in human clinical drugs. In particular, 3-substituted benzofurans are frequently found as core structures in many natural and non-natural drug molecules with proven biological activity. In order to obtain 3-substituted benzofuran derivatives with a wide range of functionalities rapidly and selectively, the development of new and efficient synthetic methods is essential. Single-electron transfer reaction is one of the most efficient ways to construct functionalized 3-substituted benzofurans, and a suitable electron donor is crucial for the success of the single-electron transfer process. However, to date, no study has reported the use of heteroatom-centered anions as direct super-electron donors for single-electron transfer reactions.   The research team of Zhichao Jin at Guizhou University has easily synthesized 3-substituted benzofuran molecules with various heteroatom functionalities by utilizing heteroatom anions as SEDs to initiate the free radical reactions in their studies. Phosphines, thiols, and anilines with different substitution patterns performed well in this intermolecular free radical coupling reaction, and the 3-substituted benzofuran products with heteroatom functionalities showed moderate to excellent yields.   Fig. 1 | Bioactivities, syntheses of 3-substituted benzofurans and SEDs for radical reactions. a Commercial drugs containing 3-substituted benzofuran structures. b Typical methods for access to 3-substituted benzofurans. c Representative organic small molecular SEDs. d Heteroatom anions as SEDs for 3-heteroalkylbenzofuran synthesis.   The generation of free radical species in the reaction system was confirmed in the study using EPR technique (CIQTEK EPR200-Plus). The EPR spectra of the mixture of 1a, HPPh2 and LDA in 25°C DME showed a signal similar to the phenyl g factor at g = 2.0023. Fig. 4 | EPR spectrum of the reaction mixtures and control experiments. a EPR spectrum of the reaction mixtures. b Feasibilities of the heteroatomic anions as SEDs for the radical reactions. c Cross-radical coupling reactions with mercaptans. d The X-band EPR spectrum of 1:2:2 stoichiometric reaction of 1a (0.1 mmol), HPPh2 (0.2 ...

Pittcon Conference and Expo 2024 Pittcon is a dynamic, transnational conference and exposition on laboratory science, a venue for presenting thelatest advances in analytical research and scientific instrumentation, and a platform for continuing education andscience-enhancing opportunity. Pitcon is for anyone who develops, buys, or sells laboratory equipmentperforms physical or chemical analyses, develops analysis methods, or manages these scientists.   · Meet us at Booth 1638: We look forward to meeting you at our booth, where we will be presenting solutions based on EPR and Scanning Electron Microscope. We will have a real working electron microscope on display, so please take the opportunity to discuss with our experts and try it out.   Date: Feb 24 - 28, 2024 Location: San Diego Convention Center,111 Harbor Dr, San Diego, CA  

APS 2024 American Physical Society March Meeting is a scientific research conference that brings together more than 13,000 physicists from around the world to showcase their work, connect with others, and discover groundbreaking physics research. Join us in 2024 for an extra special week as we celebrate the 125th anniversary of APS.   · Meet us at Booth 635: We look forward to meeting you at our booth, where we will be presenting solutions on Scanning NV Microscope (SNVM) based on NV centre technology and Electron Paramagnetic Resonance Spectrometer. Please take the opportunity to discuss with our experts. Date: Mar. 4 - 7, 2024 Location: Minneapolis Convention Center, 1301 2nd Ave S, Minneapolis, United States  

During the 2023 World Manufacturing Congress, CIQTEK launched the self-developed "Atomic Magnetometer (SpinMag-I)", a commercial Atomic Magnetometer with low energy consumption, easy to carry, and extremely high magnetic field sensitivity, which can be used for precision measurements of cardiac, cerebral, and geomagnetic magnetic fields, with the 100,000-fold increase in sensitivity compared with the classical technology (Hall effect sensors), and is expected to breed new changes in the fields of biomedicine, industrial detection, and geophysics. Opening Ceremony of the World Manufacturing Congress 2023   Atomic Magnetometer（SpinMag-I） Atomic Magnetometer（SpinMag-Ⅰ） The Atomic Magnetometer (SpinMag-I) takes advantage of the spin nature of the outer electrons of alkali metal atoms (Rb-87) and uses a pump laser as a means of manipulation to spin-polarize the alkali metal atoms. Under the action of an external weak magnetic field, the alkali metal atoms undergo Larmor progression, changing the absorption of the detection laser, thus realizing highly sensitive magnetic field measurements. The Atomic Magnetometer is characterized by high sensitivity, small size, low energy consumption, and easy portability, which will lead mankind to enter the field of magnetic sensing in scientific research, biomedicine and other fields in the future. For very weak magnetic measurements, help cardiac and brain magnetic imaging research The detection sensitivity of SpinMag-I is less than 15 fT/√Hz. The advantage of high sensitivity leads to unique applications, the most prominent of which is currently biomagnetic imaging (brain and cardiac magnetism). Magnetic brain research equipment. Image from the web.   Brain magnetism is caused by the spontaneous or induced activity of a population of brain cells, which generates a complex biological current. This signal can be captured by SpinMag-I and reconstructed to form a mathematical image according to a certain mathematical model, thus obtaining the person's brain magnetic image. Magnetic brain imaging can be used for screening of functional diseases such as epilepsy, Parkinson's, Alzheimer's, etc., and has a lower cost compared to current magnetoencephalography based on superconducting interferometer technology (SQUID). Meanwhile, the Atomic Magnetometer also provides more technological means for cutting-edge research in brain science such as brain-like computing and brain-computer interface. SpinMag-I can also be used for cardiac magnetic measurements for functional diagnosis and research of cardiovascular diseases such as myocardial ischemia. Cardiac magnetic testing based on this method has the advantages of being non-invasive and radiation-free, and is safer than current ultrasound, CT, and nuclear magnetic methods.   Product Features Miniaturization SpinMag-I probe size is approximately 30 x 16 x 12 mm3 and continues to evolve towards miniaturization. This is due to the fact that miniaturized pro...

Merry Christmas and Happy New Year!   We wish you peace, joy and prosperity throughout the coming year.   Thank you for your continued support and partnership.   As this year draws to a close, we extend our heartfelt gratitude for the trust you've placed in us and your invaluable collaboration. Wishing you and your family a wonderful Holiday Season, and we eagerly look forward to engaging in exciting new projects together in the upcoming year of 2024.

Energy storage is considered to be the last step in the development of new energy, and is the key to whether new energy can play a major role and whether it can realize the goal of "carbon neutrality". As a new type of energy storage technology, supercapacitors, with high power density, low temperature, long cycle life, wide operating temperature range, and other characteristics, can be widely used in new energy vehicles, wind power, photovoltaic power generation, as well as consumer electronics, has attracted much attention in recent years. To further improve the performance of supercapacitors, in addition to the existing technology, but also to consider the development of new technologies and new materials, the Shandong Advanced Electromagnetic Drive Technology Research Institute of Researchers Sun has deep and extensive research on this.     To meet the demand for research on various types of energy storage materials, the group of researcher Sun introduced in October 2021 a tungsten filament scanning electron microscope (SEM) independently developed by CIQTEK. It is understood that scanning electron microscopy is an important research tool in materials science, which is mainly applied in the study of material structure, morphology, composition, properties, and failure analysis. At present, the materials tested by the Institute using the CIQTEK SEM include activated carbon, metal oxides, soft carbon, hard carbon, and other electrode materials. At the same time, the group also uses SEM to analyze the causes of failure of supercapacitors and battery monomers.   "The previous electron microscope required taking a picture with a cell phone to remember the sample location before selecting the sample. The scanning electron microscope of CIQTEK has an optical navigation function, which makes it very intuitive to find the sample after it is put in. Compared with past electron microscopes, the biggest feature of the scanning electron microscope of CIQTEK is the convenient operation and high degree of automation, all the operations can be completed through the mouse point and click, with no need to operate the mouse and knob, it is convenient to move the sample and select the sample, and it is very easy to get started." Talking about the experience of using CIQTEK SEM, researcher Sun gave this example.     This perfect automation function is suitable for students without too much experience and greatly optimizes the cost of personnel training. The good experience of using the scanning electron microscope makes researcher Sun look forward to the development of the CIQTEK scanning electron microscope.

Recently, CIQTEK Field Emission Scanning Electron Microscope SEM5000 was delivered to the Major Platform Center of the Institute of Agricultural Sciences of China and officially put into use.   SEM5000 can provide morphological observation services: (1) For the observation of already dried tissue samples, you can directly book the use of the instrument reservation platform. (2) Fresh tissue samples that need to be dried and processed can be fixed with fixative and then sent to the platform for sample processing. (3) Notes on fixation of fresh tissue samples:   Samples are taken within 3 mm and fixed with glutaraldehyde (animal tissues) or FAA (plant tissues) fixative, a vacuum pump can be used to assist fixation to improve fixation efficiency. After fixation is completed, the sample is placed in a 2 ml centrifuge tube, replenished with fixative, and sent to the 115 electron microscopy room.     SEM5000 Performance Characteristics    SEM5000 is a field emission scanning electron microscope with high resolution and rich features. The advanced barrel design, high-voltage tunneling technology (SuperTunnel), and low aberration magnetic leakage-free objective lens design realize low-voltage high-resolution imaging, while magnetic samples can be applied. Optical navigation, perfect automatic functions, well-designed human-machine interaction, optimized operation, and use of the process, regardless of experience, can quickly get started to complete high-resolution shooting tasks.   1、 High-resolution, high-resolution imaging at a low accelerating voltage 2、Electromagnetic complex mirrors, reducing aberrations, significantly improving resolution at low voltages, and allowing observation of magnetic samples.3、High-voltage tunneling technology (SuperTunnel), the electrons in the tunnel can maintain high energy, reducing the space charge effect, and low voltage resolution is guaranteed. 4、The electron optical path has no cross, which effectively reduces the system aberration and improves the resolving power. 5、Water-cooled thermostatic objective lens to ensure the stability, reliability, and repeatability of the objective lens work. 6、Magnetic deflection six-aperture adjustable diaphragm, automatic switching of diaphragm aperture without mechanical adjustment, realizing rapid switching of high-resolution observation or large-beam analysis mode.   Test Sample Display      

       Recently, the group of Jiangfeng Du and Development Shi at the Key Laboratory of Microscopic Magnetic Resonance, Chinese Academy of Sciences, University of Science and Technology of China (USTC), together with Yuefeng Nie and Yurong Yang at Nanjing University, has made progress in the experimental study of scanning magnetic imaging of antiferromagnetic thin films by using diamond nitrogen-vacancy chromatography (NV chromatography for short) to perform in situ stress-tuned scanning imaging of self-supported films of antiferromagnetic BiFeO3. The research results were published as "Observation of uniaxial strain tuned spin cycloid in a freestanding BiFeO3 film" in Advanced Functional Materials [Adv. Funct. Mater. 2023, 2213725].            BiFeO3 (BFO) is an antiferromagnetic material with cycloidal order due to Dzyalonshinskii-Moriya interaction, and the mechanism of interaction between cycloidal order and stress within BFO is a major research focus in this field. Current studies have used epitaxial methods to regulate stress in BFO materials, which are difficult to modulate in situ and continuously. This makes it difficult to experimentally investigate some important issues in the magnetic-stress interaction, such as the change of magnetic order under arbitrary orientation stress and the evolution process near the phase transition of the magnetic order.          In this work, the researchers prepared a self-supported BFO film by a process of molecular beam epitaxy and soluble sacrificial layer, and performed scanning magnetic imaging of the film under stress modulation with a scanning NV microscope. The imaging results show that the cycloidal sequence twists about 12.6° at a strain of 1.5%. First principles calculations show that the experimentally observed inverse magnetic sequence twist has the lowest energy at the corresponding stress.     Figure 1. (a), (b) Real-space scanning magnetic imaging results of the BFO in the free state and at 1.5% strain. (c), (d) Fourier transform results of the scanned imaging data. (e) Statistical results of the angular distribution of the Fourier transform results in the free state and 1.5% strain state showing 12.6° of torsion.   This work is the first study of the magnetic order of BFO self-supported thin films, and the in situ modulation and high spatial resolution of the scanning imaging technique provide a new way of thinking for the study of magnetic-stress interactions. This result is valuable for the theoretical study of antiferromagnetic thin films and the application of new magnetic memory devices.     Fig. 2. The energy-pendulum line sequence period relationship curve calculated by the first nature principle. The calculated results for the pendulum line sequence direction parallel to the crystal direction are shown in blue curves, and the energy curves for the angles of 7°, 14°, ...